CORDIS Project
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This project investigates bistable rhodopsins, which are light-sensitive proteins that can switch between ON and OFF states. The aim is to understand their structure-function relationships to develop advanced optogenetic tools for controlling cellular signaling using light.
Bistable rhodopsins are naturally photosensitive G-protein coupled receptors (GPCRs) that can be toggled between stable ON and OFF states using light.
They are responsible for photosensitivity and vision across animals (including humans), and a potential source of powerful optogenetic tools enabling bidirectional control of influential intracellular signalling cascades across all body systems using light.
Lack of understanding of structure-function relationships for these proteins curtails under…
PAUL SCHERRER INSTITUT
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Germany, Berlin
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
United Kingdom, Manchester
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Freiburg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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