CORDIS Project
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This project aims to analyze the transcriptional and epigenetic states of oligodendrocyte lineage cells in healthy and diseased conditions, particularly in Multiple Sclerosis. By integrating single-cell data, the research seeks to enhance understanding of myelin repair mechanisms.
One of the current challenges in biology is the characterization of specific cell types and states.
Advances in single cell transcriptomics technologies have shown a higher heterogeneity in apparently homogeneous cell populations.
However, in order to understand cellular identity and function it is fundamental to learn from both the epigenome and the transcriptome of the single cells.
With this project I aim to study transcriptional/epigenetic states of cells from the oligodendrocyte lineage in…
KAROLINSKA INSTITUTET
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