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SONGBIRD aims to create advanced in vitro models of the blood-brain barrier to enhance drug development processes. By using microfabrication techniques, the project seeks to develop a 3D cell culture platform that mimics the barrier's structure and function, reducing reliance on animal testing.
The blood-brain barrier is a sophisticated biological barrier comprising several different cell types, structured in a well-defined order with the task to strictly control the passage of molecules - such as drugs against neurodegenerative diseases - from the blood into the brain.
To reduce the ethical and economic costs of drug development, which in EU today uses ~10 million experimental animals every year, we must develop in vitro models of the blood-brain barrier with high in vivo correlation,…
UPPSALA UNIVERSITET
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