CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the distinct roles of two isoforms of the Rho-GTPase Cdc42 in brain cells, focusing on their influence on cell movement and polarization in glioblastoma, an aggressive brain tumor. By analyzing how these isoforms affect cellular processes, the research aims to uncover potential therapeutic tar…
The Rho-GTPase Cdc42 is a key regulator of the actin and microtubule network, thereby regulating cellular processes like cell polarization and motility or membrane traffic.
Two isoforms of Cdc42 exist; one ubiquitously expressed, the other being brain-specific.
Most studies have focused on the former and specific functions of the brain-restricted variant remain obscure.
Recent observations from Etienne-Manneville’s lab uncover an isoform-specific alteration of Cdc42 expression in glioblastoma, a…
INSTITUT PASTEUR
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
