CORDIS Project
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This project seeks to develop a fast and interactive search tool for protein structures, enabling the identification of structural neighbors even in the absence of sequence similarity. The tool aims to improve navigation through the expanding Protein Data Bank.
Finding the structural neighbors of a protein is an essential task in computational structural Biology.
In cases where there is no detectable sequence similarity, the identification of structural neighbors offers a powerful approach to predicting structure and function.
State-of-the-art protein structural searches find structural neighbors by comparing a protein to all proteins in their database.
As this is an expensive computation that depends directly on the size of the database, such searches…
UNIVERSITY OF HAIFA
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