CORDIS Project
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This project explores how the mTORC1 pathway influences T cell metabolism and differentiation, aiming to develop targeted therapies for autoimmune diseases. It examines the relationship between metabolic regulation and T cell function to improve immunomodulatory treatments.
Modulating immune responses by shifting the balance of effector versus regulatory/memory T cells has significant potential as therapy for various autoimmune diseases and preventing organ transplant rejection.
The mammalian Target Of Rapamycin Complex 1 (mTORC1) has diverse effects in T cells and can function to direct T cell fate.
Direct mTORC1 inhibition provides potent immunosuppression but is associated with significant toxicity.
Dissecting the mechanisms that account for the multiple mTORC1…
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
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