CORDIS Project
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This project focuses on understanding the infection mechanisms of Staphylococcus aureus, particularly its ability to survive within immune cells. By analyzing the genetic response of phagocytes during infection using zebrafish models, it aims to uncover new strategies for treating staphylococcal diseases.
Staphylococcus aureus is able to cause a wide range of diseases, with no vaccine available and common antibiotic resistance.
It is therefore essential to better understand S. aureus pathogenesis.
Accumulating evidence indicates that an intracellular infection stage is an important step in the disease progression.
However, the mechanism of S. aureus phagocyte parasitism is currently unknown. A key question now arises as to what genes are triggered within phagocytes in response to S. aureus intern…
UNIVERSITEIT LEIDEN
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