CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project aims to create effective methods for stabilizing cyclic peptides, enhancing their biological activity and potential as drug candidates. By developing a catalytic approach for reversible stapling, it seeks to improve the delivery and efficacy of these peptides in therapeutic applications.
Cyclic (stapled) peptides often possess superior biological activity compared to their linear counterparts and are more attractive leads in drug development.
This is for several reasons: conformational rigidity (enhanced binding to target molecules and receptor selectivity), resistance to degradation by peptidases (increased stability and potency), and greater cell permeability.
Reliable strategies for peptide stapling are therefore in high demand, especially if cyclizations are reversible under…
UNIVERSITE DE STRASBOURG
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
