CORDIS Project
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This project investigates how transcription factors influence cell fate in plants, particularly in the shoot apical meristem of Arabidopsis thaliana. It aims to identify target genes regulated by key transcription factors to understand their role in stem cell maintenance and differentiation.
A central question in biology is how cell fates are established and maintained.
In general, the cellular phenotype is determined by the transcriptional program, which is orchestrated by transcription factors (TFs) – proteins that bind specific DNA sequences to activate or repress transcription.
Often, expression of a single transcription factor can lead to a radical alteration in cell fate.
Although a number of such crucial TFs have been identified, we know relatively little about TF-regulated g…
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