CORDIS Project
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This project explores how neural stem cells divide and retain aging factors, impacting neurogenesis in the brain. It aims to identify mechanisms of cellular aging and develop tools to visualize these processes, potentially informing treatments for neuropsychiatric disorders.
Neural stem/progenitor cells (NSPCs) continue to generate new neurons throughout life in distinct regions of the mammalian brain.
Adult neurogenesis has been implicated in brain function and altered neurogenesis has been associated with a number of neuropsychiatric diseases such as depression and cognitive ageing. A key feature of somatic stem cell division is the ability to divide asymmetrically and symmetrically for neurogenic and self-renewing cell division, respectively.
However, it remains…
UNIVERSITAT ZURICH
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