CORDIS Project
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This project focuses on improving the expansion protocols for hematopoietic stem cells to enhance their yield without compromising their stemness. The goal is to explore the commercial viability of this innovative approach.
There is an urgent need for improved expansion protocols for haematopoietic stem cells (HSCs).
Many studies have tried to stimulate HSC expansion by experimenting with cytokine cocktails in cell culture media.
Although these combinations of growth factors are able to increase the amount of HSCs, this happens at the cost of cell maturation: many of the cells in the final culture have lost their 'stemness' and thus their use for treatment and R&D.
Dr.
Veiga Fernandes has identified crucial surviva…
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES
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