CORDIS Project
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This project focuses on identifying long non-coding RNAs that regulate hematopoietic stem cell identity, aiming to enhance understanding of normal blood cell development and leukemia mechanisms. By constructing a comprehensive catalog of these RNAs and validating their functions, the research seeks to uncover their rol…
Hematopoietic stem cells (HSCs) are a unique population defined by their self-renewal capacity and the potential to give rise to all blood lineages. A complete understanding of the specific mechanisms controlling HSC self-renewal and multipotency is still lacking.
This knowledge is fundamental to improve ex vivo HSC expansion with therapeutic purposes and to unveil the mechanisms that promote aberrant cellular growth in leukemia.
Long non-coding RNAs (lncRNAs) are emerging as novel players of no…
INSTITUT JOSEP CARRERAS - CERCA
FUNDACIO INSTITUT DE RECERCA CONTRA LA LEUCEMIA JOSEP CARRERAS
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