CORDIS Project
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This project investigates the role of sensory nerves in recruiting stem cells during tooth development and regeneration. By using advanced genetic and imaging techniques, it aims to uncover how nerve-associated cells contribute to the formation of dental tissues.
Recently we discovered an entirely new phenomenon in developmental biology – targeted recruitment of stem cells from the pervasive peripheral nerves.
For example, we demonstrated that majority of melanocytes – our pigment cells, are born from peripheral glial cells.
To further extend this far-reaching principle we will use tooth development as a model.
Current opinion holds that sensory innervation of the tooth has a minor or no role in making a structure of the tooth during development and adul…
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