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The STEMTARGET project seeks to identify new therapeutic targets on leukemia stem cells to improve treatment options for acute myeloid leukemia. It involves characterizing cell surface targets and developing therapeutic antibodies to effectively target these cells.
Targeting Leukemia Stem CellsThe major goals of STEMTARGET is to identify novel targets on leukemic stem cells (LSCs), generate novel insights into LSC biology, and to initiate the development of LSC-directed therapeutic antibodies.
The research will focus on three specific aims: (I) To characterize novel cell surface targets on LSCs, identified by in vivo RNA interference screens. (II) To utilize an in-house developed cytokine screen for identification of cell surface targets selectively import…
MAX IV Laboratory, Lund University
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