CORDIS Project
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This project investigates how skeletal muscle stem cells respond to diseases like influenza and cancer cachexia. It explores the cellular and molecular changes in stem cells and their environment, aiming to understand their role in tissue regeneration and how they react to distant pathologies.
Coherent tissue growth and repair require an interplay between stem cells and their local and systemic environment.
The dynamics of this process remains poorly defined particularly at the intersection with disease.
Cellular quiescence is adopted by many adult stem cells, conferring them several features including a smaller cell volume and reduced metabolic demand, suggesting that quiescence preserves stem cell properties making them less responsive to external cues.
We examined the status of ske…
INSTITUT PASTEUR
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