CORDIS Project
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This research explores the relationship between cellular metabolism and the innate immune response via the STING pathway. It aims to uncover how metabolic pathways influence immune signaling, with potential implications for treating various diseases.
The innate immune response to cytosolic dsDNA via the cGAS-STING pathway has been shown to be essential in the response to various viral, bacterial and parasitic infections, in autoimmunity and in cancer.
However, the relationship between STING signalling and metabolism is currently unknown.
In recent years, our understanding of immunometabolism has also increased – it is becoming clear that metabolic adaptations are fundamental for immune responses.
Due to its role in this wide range of clinica…
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
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