CORDIS Project
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This project explores the use of cGAMP virus-like particles to enhance immune responses against cancer and viral infections. It aims to develop these particles for pre-clinical testing to validate their effectiveness in stimulating immune pathways.
Immunotherapy is a promising approach to treat cancer and infectious diseases, but innovative approaches are required.The cGAS-cGAMP-STING pathway can induce a potent immune response against viruses.
It is also implicated in antitumoral immune responses that are effective.
We have recently discovered that the small second messenger cGAMP can be packaged by viruses to stimulate immunity in target cells.
We have developed methods to produce non-infectious virus-like particles containing cGAMP (cGA…
INSTITUT CURIE
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