CORDIS Project
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This project investigates how cells in the developing nematode C. elegans make decisions about their fate in a stochastic manner, influenced by molecular noise. By employing advanced imaging techniques and mathematical modeling, it aims to uncover the mechanisms behind robust cell fate assignments during gonad developm…
In a developing embryo, each cell has to assume the correct cell fate to yield a viable adult organism.
It has become clear that the signaling networks that control development are heavily influenced by molecular noise, i.e. stochastic fluctuations on the molecular level.
Intriguingly, in many organisms cell fates are assigned in a stochastic manner.
Such stochastic cell fate decisions are thought to exploit molecular noise, using positive feedback loops to amplify noise into an all-or-nothing c…
STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN
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