CORDIS Project
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This project addresses cachexia associated with chronic kidney diseases, focusing on understanding the metabolic changes in adipose tissue and liver that contribute to body wasting. It aims to identify biomarkers for early diagnosis and explore therapeutic strategies to mitigate this serious condition.
Cachexia is a life-threatening wasting syndrome, defined by an involuntary loss of body weight, that affects a large proportion of patients with advanced chronic diseases.
Kidney diseases affect > 850 million people worldwide and represent the 10th leading cause of death.
In this context, cachexia associated with chronic kidney diseases (KCx) is a huge burden in end-stage patients with kidney replacement therapies.
Patients with KCx experience frailty, which worsens their quality of life (impact…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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