CORDIS Project
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This project investigates the role of the cytokine IL-33 in immune responses during viral infections. By identifying the cellular sources of IL-33 in lymph nodes and spleen, the research aims to enhance understanding of how this cytokine influences antiviral T cell function.
There is increasing awareness that the recently identified cytokine IL-33 is playing a key role in multiple types of infections and pathologies.
It has been recently demonstrated that IL-33 is crucial for mounting an efficient immune response against viral infections as it strongly enhances T cell responses with lack of IL-33 leading to failure in virus control. IL-33 production by stromal cells in lymph nodes (LN) and spleen is crucial for efficient viral clearance, however, the precise cellula…
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