CORDIS Project
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This project focuses on engineering human neural stem cells from skin cells to study brain disorders. It aims to create advanced 3D brain models using assembloids and integrate them with electrodes to better understand neural activity and the development of conditions like epilepsy.
Recent advances in cellular engineering allow to recruit skin cells from donors and reprogram them into neural stem cells.
These induced pluripotent stem cells (iPSC) bear the genetic code of the human patient.
Efforts to culture these cells in-vitro have been successful in creating a wide variety of 3D arrangements called neurospheres.
Because the human central nervous system is by and large inaccessible at all developmental stages, these functional tissue preparations are invaluable.
Furthermo…
FORSCHUNGSZENTRUM JULICH GMBH
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United States, Stanford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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