CORDIS Project
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This project utilizes CRISPR-Cas9 technology to target specific mutations in the KRAS gene associated with lung cancer. By generating a transgenic mouse model, the research aims to evaluate the potential of gene editing as a therapeutic strategy to disrupt cancer progression.
Genome editing has enriched our understanding of mechanisms of the human pathology.
Genome editing took a significant advance with the recent development of the CRISPR-Cas9 technology. CRISPR is an acronym for:
Clustered Regularly Interspaced Short Palindromic Repeats and it is an adaptation of a prokaryotic functional system.
It uses a single guide RNA to direct Cas9 activity to a specific part of the genome, therefore, this system can be used for gene editing and regulation.Cancer is a genetic…
UNIVERSIDAD DE GRANADA
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