CORDIS Project
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This project aims to develop a sustainable method for synthesizing amides, which are crucial in drug manufacturing. By combining biocatalytic and organocatalytic strategies, the project seeks to create a one-pot reaction that minimizes environmental impact and enhances efficiency in amide production.
Amide bond formation is fundamental to the synthesis of a wide array of amide-containing drugs.
Conventional methods for amide synthesis typically rely on stoichiometric activating agents that are harmful to the environment and less sustainable.
Therefore, there is an urgent need for more efficient, selective, and sustainable methods for amide synthesis.
This project addresses these challenges by designing a novel bio-organocatalytic cascade reaction for the stereoselective synthesis of amides,…
UNIVERSITEIT VAN AMSTERDAM
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