CORDIS Project
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This project aims to understand the role of protein N-glycosylation in bone health and its implications for osteoporosis. By studying genetic mutations in mice, it seeks to identify new therapeutic targets for improving bone strength and addressing metabolic issues related to obesity.
Osteoporotic bone loss due to aging or disease is a major health issue that affects hundreds of millions of people worldwide and costs tens of billions of euros each year.
Since current osteoporosis medication only reduces fracture risk by 25-50%, there is an urgent need to define new pathways that control bone remodelling and strength in order to identify new therapeutic targets.
Via the ‘Mouse Genetics Project’ consortium, we identified a mutation in one of the enzymes involved in the N-linked…
GENOME RESEARCH LIMITED
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