CORDIS Project
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This project aims to develop a new, efficient method for synthesizing sulfonamides in a single operation using readily available reagents. The approach focuses on a three-component reaction that minimizes waste and energy use, potentially improving pharmaceutical production processes.
Sulfonamides are functional groups that feature in a significant number of pharmaceuticals, with applications in a variety of indications.
Conventional syntheses of sulfonamides usually involve two or three synthetic operations, and often feature low-yielding steps.
The chemistry involved also limits the substrates that can be converted to sulfonamides.
This proposal seeks to develop an alternative synthesis of sulfonamides; the proposed synthesis will be achieved in a single operation, emplo…
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