CORDIS Project
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This research investigates the role of host SUMO pathways in influenza virus replication to develop new antiviral strategies. By understanding how SUMO proteins interact with viral components, the project aims to identify potential therapeutic targets that minimize drug resistance.
Influenza viruses cause a significant seasonal disease burden and continually threaten to initiate human pandemics.
Antivirals are available for treatment of influenza, however drug-resistant viruses often emerge.
Thus, there is urgent need to develop new antivirals with lower chances of selecting resistance.
As viruses rely extensively on cellular functions, one way to minimise resistance is to target new antivirals against host factors.
This concept requires a fundamental understanding of mech…
University of Zurich
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United Kingdom, Glasgow
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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