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The Superantibodies project aims to create synthetic recognition elements that mimic natural antibodies by combining biomolecular techniques and organic chemistry. It focuses on designing peptides that can bind specifically to antigens, ultimately leading to improved synthetic antibodies with enhanced affinity.
The project “Superantibodies” encompasses an interdisciplinary approach to accomplish the first instance of a biohybrid, yet fully synthetic three dimensional recognition element by converging the benefits of natural biorecognition with those of a synthetic approach.
The bio-inspired concept is modelled on the antibody binding site whose binding capacity is the result of a defined three-dimensional structure in which loops of polypeptides cooperatively interact with the antigen through specific…
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