CORDIS Project
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The SupraVir project develops innovative virus inhibitors using multivalent supramolecular assemblies that adapt to various virus shapes and mutations. By mimicking host cell surface receptors, these inhibitors aim to provide broad protection against a wide range of viral infections, enhancing future pandemic preparedn…
Background:
Viral pandemics pose great risks to current and future human health and global trade.
Newly emerging viruses can display a broad variety of shapes, such as spherical or filamentous, and spike proteins have different lengths and densities, as seen in coronaviruses and influenza viruses.
Viruses can mutate rapidly under evolutionary pressure, resulting in changes to antigen epitopes and reduced efficacy of drugs and vaccines.
These variances between viruses and across mutations present…
FREIE UNIVERSITAET BERLIN
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