CORDIS Project
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This project focuses on understanding bacterial adhesin proteins and their unique sugar modifications, which are crucial for bacterial infection. By developing methods to visualize and quantify these sugars, the project aims to identify new antibacterial targets and enhance treatment strategies against resistant bacter…
With bacteria increasingly resistant to current antibiotics, new strategies to fight infection are needed.
Bacterial adhesin proteins, which play an important role in the establishment of infection, appear to be promising targets for novel therapies.
Adhesins enable the first contact between bacteria and host cells.
We know that some adhesins are modified with highly unique sugars that are important for adhesin stability and adherence.
However, we do not know how widespread this modification is,…
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