CORDIS Project
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This project focuses on developing innovative cancer diagnostics by targeting specific carbohydrate-neoantigens present on tumor cells. By creating highly specific antibodies against these altered sugar patterns, the project aims to improve early detection and therapy optimization for cancer patients.
Cancer is a leading cause of death worldwide and novel diagnostic and therapeutic approaches are much needed.
All living cells are covered with a dense layer of sugar-coat that is altered in cancer.
One of the hallmarks of cancer is the expression of aberrant cell surface glycosylation patterns compared to normal cells.
Current antibody-based assays against cancer glycans are commonly utilized to monitor clinical response to therapy, however none is useful for early detection or diagnosis due to…
TEL AVIV UNIVERSITY
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