CORDIS Project
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This project employs a systems biology approach to study the bone marrow stem cell niche, focusing on cellular and molecular interactions during acute myeloid leukemia. It aims to map the tissue's complexity and identify potential therapeutic targets.
Our understanding of the different layers of organization in tissues remains limited.
Stem cell niches offer a tightly controlled environment and a unique opportunity to look into this question.
Reductionist approaches have been proven highly efficient dissecting the complexity of stem cell niches in a unidirectional fashion.
However, this approach fails to recognize the tri-dimensional complexity of tissue organization.
Hence we propose a systems biology approach based on low input and single c…
FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA
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