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The SYMBIOSES project explores the potential of incorporating other cells as endosymbionts to introduce new metabolic traits into host cells. This research aims to develop methods for creating cellular compartments that enhance metabolic functions, focusing on nitrogen and carbon fixation.
The introduction of new functionalities into cells is a challenge, but it offers tremendous opportunities.
While some traits may be acquired through lateral gene transfer and be immediately operational, others are complex and require comprehensive rewiring of the host cell due to lack of orthogonality. A powerful strategy used by cells to acquire new properties is the incorporation of other dedicated cells as endosymbionts that may eventually become organelles in the course of evolution, the mos…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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