CORDIS Project
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This project explores the use of genetically modified microbial symbionts in arthropods to prevent disease transmission. It focuses on paratransgenesis, which involves manipulating symbiotic bacteria to express anti-pathogen molecules, particularly in mosquitoes.
Advances in biotechnology propose innovative tools particularly relevant for public health application by genetic manipulation of microbial symbionts of arthropod vectoring disease.
The symbiont engineering prevents the transmission of pathogens to human by interfering with their stage within the arthropod, thorough the expression of anti-pathogen effector molecules.
This approach, defined paratransgenesis is simpler than the proposed engineering of the vector itself (transgenesis) and implies m…
UNIVERSITA DEGLI STUDI DI CAMERINO
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