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SyMPaBiome focuses on creating a synbiotic product combining live beneficial bacteria and prebiotics to improve gut health in Parkinson's disease patients. The project aims to reduce intestinal inflammation, enhance gut barrier function, and lower harmful metabolite production linked to disease progression.
SyMPaBiome aims to develop a synbiotic, a mixture of live biotherapeutic bacteria and a prebiotic, to modulate the Parkinson’s disease (PD) microbiome, with the threefold aim to decrease (1) the intestinal (neuro-)inflammation and (2) gut permeability associated with PD, as well as to (3) decrease the production of a recently discovered archaeal metabolite linked to PD development and progression.
This synbiotic regimen will be the first mechanism-based synbiotic formulation, underpinned by fun…
UNIVERSITE DU LUXEMBOURG
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