CORDIS Project
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This project explores how hair cell activity in the cochlea influences the precise wiring of auditory neurons. It aims to understand the mechanisms behind this process, which could inform treatments for hearing-related disorders.
Humans are able to discriminate sounds with frequencies that are separated by no more than 0.1%.
This level of performance arises from the exceptional sensory capacities of our cochlea, which detects stimuli through an array of sensory hair cells, spatially organized to follow a gradient of preferred frequency (a tonotopic map).
This map is conserved downstream of the cochlea, implying that cochlear neurons must connect hair cells to the cochlear nuclei in the brain with high precision so as to…
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