CORDIS Project
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This project explores the interactions between neurons and pancreatic cancer cells, revealing direct synaptic connections that enhance tumor invasiveness. By analyzing these neuron-cancer networks, the research aims to uncover new therapeutic strategies for pancreatic cancer treatment.
The nervous system has recently been identified to play a central role in cancer pathogenesis, and this discovery has given birth to the burgeoning field of “cancer neuroscience”.
Neurons and cancer cells outside the brain are known to communicate over paracrine signals, However, we recently discovered direct synaptic connections between sensory nerve endings and cancer cell membrane in a cancer outside the brain, i.e., pancreatic ductal adenocarcinoma (PDAC).
These synaptic sites exhibit a sele…
KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
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