CORDIS Project
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This study explores how memory is stored at the synaptic level, focusing on local protein synthesis in dendrites. It aims to understand the relationship between synaptic activity and protein dynamics, which are crucial for memory formation and plasticity.
Understanding how and where our memory is stored is a long sought-after task.
It is accepted that proteins at synapses play a role in capturing and maintaining memory.
It is now clear that synapses possess the capacity for local protein synthesis, and that dendritic protein synthesis is required for many forms of long-term synaptic potentiation (LTP) and plasticity.It remains unclear over what spatial scale local translation can be regulated and stimulated.
Moreover, the location of specific tra…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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