CORDIS Project
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This research focuses on understanding how protein levels at synapses regulate neural function and stability. It aims to explore the molecular mechanisms behind synaptic proteostasis and its implications for neurological diseases using genetic and electrophysiological methods.
While many neurons live for decades, the proteins that determine neural function have half-lives of hours to weeks.
On the one hand, this allows for plastic changes during development and learning.
On the other hand, this poses the question of how stable neural function can be achieved and maintained at all.
Several neurological diseases, such as epilepsy or migraine, have been linked to uncontrolled neural function.
However, the molecular mechanisms that stabilize nervous system function are po…
UNIVERSITAT ZURICH
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