CORDIS Project
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This project aims to create a comprehensive map of genetic interactions in Drosophila cells, focusing on how genes interact within signaling networks. By employing novel methodologies, it seeks to enhance our understanding of complex biological systems and their underlying genetic factors, with potential applications i…
The genetics underlying phenotype-genotype relationships during development and disease is often complex with many genes contributing to a particular phenotypic outcome.
While forward genetic screens have uncovered many mutations that are limiting at a particular stage or tissue, the majority of genes in most genomes remain genetically untouched.
Recent studies in model organisms, in particular in yeast, have provided evidence for the existence of pervasive genetic interactions with large effect…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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