CORDIS Project
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This project investigates the molecular mechanisms governing synaptic development and plasticity in humans. By studying specific genes and employing various experimental techniques, it aims to uncover how human synapses differ from those of other species, contributing to our understanding of cognitive abilities.
The synapse is a nanoscale machine, which transfers, integrates and stores information in brain circuits.
Its function relies on multimolecular networks of interactions whose composition and dynamics shape synaptic transmission. A large body of evidence indicates that synapses specialized in humans.
Human synapses are more densely distributed along dendrites and their period of maturation is protracted compared to rodent or non-human primate synapses.
The rules governing their plasticity also di…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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