CORDIS Project
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This project focuses on the role of the Scribble protein in neuronal development, particularly in the formation and function of synapses. It aims to understand how this protein interacts with the cytoskeleton and adhesion molecules in brain cells.
SynPCP is a MSCA-IF-EF project in Neuroscience aimed at deciphering spatiotemporal mechanisms controlled by the planar cell polarity (PCP) protein Scribble (Scrib) in spine during specification and morpho-fonctional plasticity that depend on the dynamics of the actin cytoskeleton and trans-synaptic adhesions.
Growing evidences suggest that PCP signaling is fundamental for neuronal development mechanisms, including dendrite morphogenesis and synaptogenesis. PCP signaling defects have been linked…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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