CORDIS Project
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This project investigates the biosynthetic pathways of vinblastine, an anti-cancer compound from the plant Catharanthus roseus. It aims to identify key genes involved in its production and develop high-yield platforms for metabolite synthesis using yeast and tobacco.
Nature produces a spectacularly diverse array of complex molecules that are exploited for many applications.
Elucidating the biosynthetic pathways that are used to construct these complex molecules allows implementation of metabolic engineering or synthetic biology strategies that can dramatically improve production levels of these compounds.
Moreover, identifying the biosynthetic genes facilitates study of the unprecedented biochemistry harboured within these specialised metabolic pathways.
Unf…
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United Kingdom, Norwich
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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