CORDIS Project
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This project investigates the role of synaptic vesicle priming in neuronal signaling and its impact on brain function. It aims to understand the mechanisms behind synaptic plasticity and how they relate to behavior, using advanced genetic and electrophysiological techniques.
Neuronal signalling via synaptic vesicle (SV) fusion is the fastest membrane fusion event in mammalian cells.
Its speed and the ability of presynapses to sustain SV fusion at high stimulation rates are key requirements for brain function.
Plastic changes of SV fusion rates have long been thought to control complex brain processes such as working memory, but the link between presynaptic plasticity and complex brain functions remains hypothetical. A key determinant of presynaptic efficacy is that…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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