CORDIS Project
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The SynSys project focuses on understanding the molecular mechanisms of central nervous system disorders by analyzing synaptic signaling. It aims to identify potential therapeutic targets through systems-level analysis of protein interactions.
Major disorders of the Central Nervous System (CNS) affect one in three people in the developed world, often seriously disable the affected individual, and together account for the single largest burden on the healthcare systems of the EU.
Most of these disorders act at the neuronal synapse, a cellular organelle comprising in the order of 2000 proteins.
Pleiotropy, cross-talk between proteins and the complexity of the underlying signalling complexes pose a significant challenge to dissecting the…
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