CORDIS Project
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This project investigates the genetic mechanisms of crossover distribution during meiosis in eukaryotes, focusing on Arabidopsis. It aims to manipulate recombination hotspots to enhance genetic diversity and improve crop breeding strategies.
The majority of eukaryotes reproduce sexually via meiosis.
During meiosis homologous chromosomes pair and undergo reciprocal genetic exchange termed crossover.
Meiotic recombination is a major evolutionary force and has a profound effect on patterns of genetic diversity in sexual species.
Crossovers distributions are highly non-random and are typically focused in narrow hotspots.
Study of hotspots throughout eukaryotes has revealed combinations of genetic and epigenetic factors that contribute t…
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