CORDIS Project
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This project investigates the genetic factors contributing to Type 2 diabetes, focusing on the role of the CREBBP protein in disease predisposition. It aims to integrate genetic data to better understand the mechanisms behind T2D.
Type 2 diabetes (T2D) represents a major challenge to global health.
In recent years, over 60 genetic loci have been confidently implicated in T2D predisposition: however, there has been only limited progress in defining the biological mechanisms responsible.
Recent work led by the host institution has revealed that these T2D-associated loci are substantially enriched for genes whose protein products interact with CREBBP, identifying this transcriptional co-activator as a key node linking proces…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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