CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates transcriptional adaptation, a process where certain mutations trigger changes in gene expression to compensate for genetic damage. It explores the mechanisms behind this process in various organisms, including zebrafish and mice, aiming to understand its implications for genetic robustness and…
Organisms utilize several mechanisms to compensate for the damaging consequences of genetic perturbations.
One such mechanism is the newly identified process of transcriptional adaptation (TA): in this process, certain deleterious mutations trigger the transcriptional modulation of so-called adapting genes.
In some cases, e.g., when one of the upregulated genes is functionally redundant with the mutated gene, TA leads to functional compensation.
Notably, unlike other modes of compensation, TA…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
