CORDIS Project
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This project investigates the communication between tanycytes, a type of glial cell in the brain, and neurons that regulate energy balance. By understanding how these cells interact, the research aims to uncover mechanisms that could lead to new treatments for obesity and type-2 diabetes.
The escalating pandemic of obesity and type-2 diabetes represents one of the most pressing and costly biomedical challenges confronting modern society.
The brain's impaired ability to sense and respond to variations in energy homeostasis is increasingly recognized as playing a role in the pathophysiology of these disorders.
By sensing the nutritional status of the organism, distinct neural cell populations –including neurons and glia present in the arcuate nucleus of the hypothalamus (ARH)– tigh…
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