CORDIS Project
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This project investigates the role of reactive oxygen species in multidrug resistance in glioblastoma. By combining PhotoActivated ChemoTherapy and a chemogenetic tool, it aims to enhance treatment efficacy and understand cancer cell responses to oxidative stress.
Cancer therapy faces significant challenges due to multidrug resistance (MDR), which reduces the effectiveness of chemotherapeutic agents. A key factor influencing MDR is the altered redox state within cancer cells, characterized by varying levels of reactive oxygen species (ROS).
Understanding the dynamics of ROS is crucial, as they can both promote and inhibit tumor progression.
Glioblastoma, a highly aggressive and treatment-resistant brain cancer, exemplifies the challenges associated with M…
UNIVERSITEIT LEIDEN
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Leiden University Medical Center
Netherlands, Leiden
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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