CORDIS Project
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This project focuses on developing anti-virulence drugs to combat tuberculosis by targeting the Mycobacterium tuberculosis pathogen's ability to evade the host immune system. The research aims to identify critical host cell signaling pathways involved in the disease's progression, potentially leading to more effective…
While short course chemotherapy for drug-susceptible tuberculosis (TB) remains effective, it is relatively inefficient by modern pharmaceutical standards and universally menaced by the dissemination of multidrug-resistant (MDR), extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis (M.tb) and synergy with the HIV/AIDS pandemic.
Since one third of the world’s population is latently infected with M.tb, successful anti-TB drugs must be able to eliminate persistent bacilli from the…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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